Syk depletion effect on breast epithelial cell line
Transcriptomics Dataset
FAIR Metrics
0 evaluations
General Information
AccessionGSE16200
TitleSyk depletion effect on breast epithelial cell line
DescriptionAnalysis of MCF10A breast epithelial cells depleted for Syk. Progressive loss of Syk mRNA occurs during breast tumor development. Results provide insight into Syks tumor suppressor function and role in normal breast development.
Landing Pagehttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE16200
RepositoryGene Expression Omnibus
Tools used to analyze the dataset

Keyword
Dataset Accession

Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Canned Analyses generated with the dataset

Dataset Accession
Tool Name
Direction
Cell Type
Pert Type
Geneset

Small molecules which mimic SYK KD
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse SYK KD
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic SYK Depletion
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse SYK Depletion
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic SYK KD
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse SYK KD
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic SYK KD
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse SYK KD
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic SYK DEPLETION
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse SYK DEPLETION
The L1000 database was queried in order to identify small molecule perturbations which rev...
...
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