Small molecules which reverse IKBKB transient expression of constitutively active IKKβ(E
Canned Analysis
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General Information
AccessionDCA00022116
TitleSmall molecules which reverse IKBKB transient expression of constitutively active IKKβ(E
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by IKBKB transient expression of constitutively active IKKβ(E in the cell line: Reh malignancy: non-Hodgkin lymphoma cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d236a0e467bea600fbb954
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:2442
Cell Typecell line: Reh malignancy: non-Hodgkin lymphoma
Gene Symbol (human)IKBKB
Gene Symbol (mouse)Ikbkb
Organismhuman
Perturbation Typetransient expression of constitutively active IKKβ(E
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM502627, GSM502628
Perturbed SamplesGSM502631, GSM502632
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE20115
Gene Expression Omnibus
CBFA2T3 knockdown and ectopic IKKbeta(EE) expression effect on Non-Hodgkin's lymphoma Reh cells
14
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