Small molecules which mimic PPARGC1A KD
Canned Analysis
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General Information
AccessionDCA00022797
TitleSmall molecules which mimic PPARGC1A KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by PPARGC1A KD in the A375P melanoma cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20627e467bea600fba430
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorjoagap
CREEDS IDgene:3090
Cell TypeA375P melanoma cells
Gene Symbol (human)PPARGC1A
Gene Symbol (mouse)Ppargc1a
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM904726, GSM904727
Perturbed SamplesGSM904724, GSM904725, GSM904728, GSM904729, GSM904730, GSM904731
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE36879
Gene Expression Omnibus
PGC1alpha depletion effect on melanoma cell line
49
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