Small molecules which reverse BRWD1 Mutation
Canned Analysis
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General Information
AccessionDCA00023208
TitleSmall molecules which reverse BRWD1 Mutation
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by BRWD1 Mutation in the Oocytes cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d228b8e467bea600fbb332
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorjoagap
CREEDS IDgene:3123
Cell TypeOocytes
Gene Symbol (human)BRWD1
Gene Symbol (mouse)Brwd1
Organismmouse
Perturbation TypeMutation
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1367375, GSM1367376, GSM1367377
Perturbed SamplesGSM1367378, GSM1367379, GSM1367380
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE56724
Gene Expression Omnibus
Effect of Brwd1 mutation on the mouse oocyte transcriptome
7
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