Small molecules which reverse NOS3 KO
Canned Analysis
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General Information
AccessionDCA00023808
TitleSmall molecules which reverse NOS3 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by NOS3 KO in the heart cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d218f2e467bea600fbac76
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
CREEDS IDgene:803
Cell Typeheart
Gene Symbol (human)NOS3
Gene Symbol (mouse)Nos3
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM35562, GSM35563, GSM35564, GSM35566
Perturbed SamplesGSM35542, GSM35543, GSM35561
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE1988
Gene Expression Omnibus
Heart failure and nitric oxide
12
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