Small molecules which mimic PPARD KO
Canned Analysis
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General Information
AccessionDCA00023815
TitleSmall molecules which mimic PPARD KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by PPARD KO in the pancreas (islets, PDX1-expressing cells) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21a56e467bea600fbad10
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcarlfulp
CREEDS IDgene:81
Cell Typepancreas (islets, PDX1-expressing cells)
Gene Symbol (human)PPARD
Gene Symbol (mouse)Ppard
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM401525, GSM401526, GSM401527
Perturbed SamplesGSM401528, GSM401529, GSM401530
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE16048
Gene Expression Omnibus
Pancreatic-specific PPAR-beta deletion effect on pancreatic beta-cells
7
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