Small molecules which reverse RB1 Deficiency
Canned Analysis
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General Information
AccessionDCA00023902
TitleSmall molecules which reverse RB1 Deficiency
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by RB1 Deficiency in the Prostate epithelial cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22f34e467bea600fbb60e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:932
Cell TypeProstate epithelial cells
Gene Symbol (human)RB1
Gene Symbol (mouse)Rb1
Organismmouse
Perturbation TypeDeficiency
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM14671, GSM14672
Perturbed SamplesGSM14675, GSM14676
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE934
Gene Expression Omnibus
Retinoblastoma-deficient prostate epithelial cells, and effect of serum
14
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