Retinoblastoma-deficient prostate epithelial cells, and effect of serum
Transcriptomics Dataset
FAIR Metrics
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General Information
AccessionGSE934
TitleRetinoblastoma-deficient prostate epithelial cells, and effect of serum
DescriptionComparison of retinoblastoma-deficient (Rb-/-) and control wild type prostate epithelial cell lines maintained in RPMI-1640 medium supplemented with 5%% fetal bovine serum, or without serum for 48 hours.
Landing Pagehttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE934
RepositoryGene Expression Omnibus
Tools used to analyze the dataset

Keyword
Dataset Accession

Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Canned Analyses generated with the dataset

Dataset Accession
Tool Name
Direction
Pert Type
Geneset

Small molecules which mimic RB1 KO
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse RB1 KO
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic RB1 Deficiency
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse RB1 Deficiency
The L1000 database was queried in order to identify small molecule perturbations which rev...
Enrichment analysis of genes dysregulated in RB1 KO
An enrichment analysis was performed on the top most dyresgulated genes determined by appl...
Enrichment analysis of genes dysregulated in RB1 Deficiency
An enrichment analysis was performed on the top most dyresgulated genes determined by appl...
Interaction network and enrichment analysis of genes downregulated in RB1 KO
The analysis explores the gene interaction network and pathway enrichment of the top 50 mo...
Interaction network and enrichment analysis of genes upregulated in RB1 KO
The analysis explores the gene interaction network and pathway enrichment of the top 50 mo...
Interaction network and enrichment analysis of genes downregulated in RB1 Deficiency
The analysis explores the gene interaction network and pathway enrichment of the top 50 mo...
Interaction network and enrichment analysis of genes upregulated in RB1 Deficiency
The analysis explores the gene interaction network and pathway enrichment of the top 50 mo...
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