Enrichment analysis of genes dysregulated in AIRE NULL MUTATION
Canned Analysis
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General Information
AccessionDCA00024177
TitleEnrichment analysis of genes dysregulated in AIRE NULL MUTATION
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between AIRE NULL MUTATION cells and control cells in the Medullary epithelial cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3093550
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:1172
Cell TypeMedullary epithelial cells
Gene Symbol (human)AIRE
Gene Symbol (mouse)Aire
Organismmouse
Perturbation TypeNULL MUTATION
Characteristic Direction parameters
Control SamplesGSM304908, GSM304909, GSM304910
Perturbed SamplesGSM304911, GSM304912, GSM304913
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE12073
Gene Expression Omnibus
Aire ectopic expression effect on pancreatic islet beta cells
14
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