Enrichment analysis of genes dysregulated in H3F3A Mutation (G34R - mutation of key residues in histone H3.3)
Canned Analysis
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General Information
AccessionDCA00024229
TitleEnrichment analysis of genes dysregulated in H3F3A Mutation (G34R - mutation of key residues in histone H3.3)
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between H3F3A Mutation (G34R - mutation of key residues in histone H3.3) cells and control cells in the Pediatric glioblastoma (GBM) tumors cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3095336
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:1228
Cell TypePediatric glioblastoma (GBM) tumors
Gene Symbol (human)H3F3A
Organismhuman
Perturbation TypeMutation (G34R - mutation of key residues in histone H3.3)
Characteristic Direction parameters
Control SamplesGSM855946, GSM855948, GSM855949, GSM855950, GSM855951, GSM855952, GSM855953, GSM855954, GSM855955, GSM855956, GSM855958, GSM855959, GSM855960, GSM855961, GSM855962, GSM855963, GSM855964, GSM855965
Perturbed SamplesGSM855942, GSM855943, GSM855944
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Datasets used in the analysis
Keyword
Tool Name
GSE34824
Gene Expression Omnibus
Pediatric glioblastoma brain tumors: histone H3.3 mutations
14
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