Interaction network and enrichment analysis of genes upregulated in amyotrophic lateral sclerosis
Canned Analysis
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General Information
AccessionDCA00032740
TitleInteraction network and enrichment analysis of genes upregulated in amyotrophic lateral sclerosis
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by amyotrophic lateral sclerosis and healthy control cells in the Spinal cord grey matter - sporadic ALS cell type.
Analysis URLhttp://genemania.org/#/search/human/MT2A|MT1HL1|NPIPB5|APOE|FTL|VIM|CD74|LOC100130553|PSAP|RPSAP19|GNAS|RPLP2|RPLP1|IFITM2|RPS25|RPS16|RPLP0|RPL23AP74|RPL4|B2M|RPS15|IFITM1|RPL18A|CD99|RPL19
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curator
CREEDS ID
Cell Type
DO ID
Disease Name
Organism
UMLS CUI
Characteristic Direction parameters
Gene Set
Gene Set Size
Control Samples
Perturbed Samples
Tools used in the analysis

Keyword
Dataset Accession

GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis

Keyword
Tool Name

GSE833
Amyotrophic lateral sclerosis (Lou Gehrig's Disease)
14
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