Interaction network and enrichment analysis of genes upregulated in abdominal aortic aneurysm
Canned Analysis
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General Information
AccessionDCA00032746
TitleInteraction network and enrichment analysis of genes upregulated in abdominal aortic aneurysm
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by abdominal aortic aneurysm and healthy control cells in the Aorta cell type.
Analysis URLhttp://genemania.org/#/search/human/TIMM17A|STRAP|DMRTB1|NSMCE1|LOC100288893|SIK3|RPS19BP1|ARNT2|ZBTB3|BTNL9|ZC3H8|PFDN4|GRASP|TM4SF5|DLD|SV2C|B3GAT2|TGOLN2|PLCB3|UFSP1|SNAI3|SLC34A1|RSU1|LIN28A|IFNAR1
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:1011
Cell TypeAorta
DO IDDOID:7693
Disease Nameabdominal aortic aneurysm
Organismhuman
UMLS CUIC0162871
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM1150703, GSM1150704, GSM1150705, GSM1150706, GSM1150707, GSM1150708, GSM1150709, GSM1150710
Perturbed SamplesGSM1150689, GSM1150690, GSM1150691, GSM1150692, GSM1150693, GSM1150694, GSM1150695, GSM1150696, GSM1150697, GSM1150698, GSM1150699, GSM1150700, GSM1150701, GSM1150702
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE47472
Gene Expression Omnibus
Differential gene expression in the proximal neck of human abdominal aortic aneurysm
7
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