Interaction network and enrichment analysis of genes downregulated in Carcinoma in situ of small intestine
Canned Analysis
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General Information
AccessionDCA00032907
TitleInteraction network and enrichment analysis of genes downregulated in Carcinoma in situ of small intestine
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by Carcinoma in situ of small intestine and healthy control cells in the Intestinal Epithelium cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Pigr|Igkv6-23|Defa2|H2afv|St3gal4|Lgals4|Cps1|Atpif1|Krt20|Tpt1|Rpl18|Acaa1a|Fcgbp|Tff3|Fabp2|Cyp4v3|Gm15308|Atp5a1|Otc|Acaa2|Rpl5|Zg16|Calml4|Gm15284|Muc3
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:119
Cell TypeIntestinal Epithelium
Disease NameCarcinoma in situ of small intestine
Organismmouse
UMLS CUIC0686083
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM6191, GSM6192, GSM6193, GSM6194, GSM6195, GSM6196
Perturbed SamplesGSM6202, GSM6203, GSM6204, GSM6205, GSM6206
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE422
Gene Expression Omnibus
Colon cancer
36
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