Interaction network and enrichment analysis of genes upregulated in Infection by Yersinia enterocolitica
Canned Analysis
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General Information
AccessionDCA00032924
TitleInteraction network and enrichment analysis of genes upregulated in Infection by Yersinia enterocolitica
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by Infection by Yersinia enterocolitica and healthy control cells in the macrophage cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Ccl4|Rsad2|Ccl3|Tnf|Cxcl10|Ccl2|Ccl5|Oasl1|Ifit1|Ccrl2|Cxcl1|Ppp1r15a|Rgs1|Ccl7|Cxcl2|Ifih1|Tnfaip3|E430024C06Rik|Atf3|Ifrd1|Tnfsf9|Plk2|Ifit2|Cd274|Ifnb1
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:127
Cell Typemacrophage
Disease NameInfection by Yersinia enterocolitica
Organismmouse
UMLS CUIC0238528
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM64988, GSM64989, GSM64990, GSM65007, GSM65008, GSM65009
Perturbed SamplesGSM64995, GSM64996, GSM64997, GSM65001, GSM65002, GSM65003, GSM65013, GSM65014, GSM65015, GSM65019, GSM65020, GSM65021
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE2973
Gene Expression Omnibus
IFN-gamma and host genetic background effect on Yersinia enterocolitica infected macrophages
7
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