Interaction network and enrichment analysis of genes upregulated in bacterial infectious disease
Canned Analysis
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General Information
AccessionDCA00032932
TitleInteraction network and enrichment analysis of genes upregulated in bacterial infectious disease
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by bacterial infectious disease and healthy control cells in the Leukocyte - Monocyte - Macrophage (MMHCC) cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Rsad2|Ifi204|Pla2g7|Saa3|Ms4a6b|Ifit1|Arg1|Fgl2|Xpa|Fcgr1|Cxcl10|Cfb|Hmox1|Ms4a4d|Irf7|Serpinb2|Ifit2|Il1rn|Anks6|Epsti1|OTTMUSG00000010754|Ccrl2|Cep170|1700021F02Rik|Tdrd7
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:133
Cell TypeLeukocyte - Monocyte - Macrophage (MMHCC)
DO IDDOID:104
Disease Namebacterial infectious disease
Organismmouse
UMLS CUIC0004623
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM4635, GSM4640, GSM4649
Perturbed SamplesGSM4639, GSM4644, GSM4648
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE6435
Gene Expression Omnibus
LPS timecourse
7
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