Interaction network and enrichment analysis of genes downregulated in Acute Lung Injury
Canned Analysis
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General Information
AccessionDCA00032977
TitleInteraction network and enrichment analysis of genes downregulated in Acute Lung Injury
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by Acute Lung Injury and healthy control cells in the Lung Tissue cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Inmt|Scgb3a2|Bpifa1|Cyp2f2|Cbr2|Wfdc2|Aldh1a1|Scgb1a1|Sftpb|Eef1a1|Scgb3a1|Actc1|Neat1|Tmsb4x|Gm4076|Sepp1|Rps12|Mettl7a2|Sdpr|Cav1|Cyp2s1|Myl7|Rpl39-ps|Rpl31-ps17|Rps27rt
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:152
Cell TypeLung Tissue
Disease NameAcute Lung Injury
Organismmouse
UMLS CUIC0242488
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM29706, GSM29707, GSM29708
Perturbed SamplesGSM29709, GSM29710, GSM29711
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE1871
Gene Expression Omnibus
Inflammatory lung injury and effect of simvastatin
14
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