Interaction network and enrichment analysis of genes upregulated in Acute Lung Injury
Canned Analysis
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General Information
AccessionDCA00033024
TitleInteraction network and enrichment analysis of genes upregulated in Acute Lung Injury
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by Acute Lung Injury and healthy control cells in the Whole blood cell type.
Analysis URLhttp://genemania.org/#/search/human/MNDA|DEFA1B|CST7|LYZ|ALAS2|ARG1|OAZ1|MMP9|TMSB4XP8|NQO2|CD177|S100A9|PFN1|NCOA4|UBA52|SLC4A1|LCN2|PLBD1|GMFG|TSPO|EEF1A1P9|OLFM4|CORO1A|HMGB2|TALDO1
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:168
Cell TypeWhole blood
Disease NameAcute Lung Injury
Organismhuman
UMLS CUIC0242488
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM265004, GSM265006, GSM265008, GSM265009, GSM265011, GSM265014, GSM265016, GSM265018, GSM265019, GSM265021, GSM265022, GSM265023, GSM265024, GSM265026, GSM265027, GSM265028, GSM265029, GSM265030, GSM265031, GSM265032, GSM265033
Perturbed SamplesGSM264753, GSM264987, GSM264988, GSM264989, GSM264990, GSM264991, GSM264992, GSM264994, GSM264995, GSM264996, GSM264998, GSM265000, GSM265001
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE10474
Gene Expression Omnibus
Microarray Analysis of Acute Lung Injury
7
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