Interaction network and enrichment analysis of genes downregulated in Pseudomonas Infection
Canned Analysis
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General Information
AccessionDCA00033033
TitleInteraction network and enrichment analysis of genes downregulated in Pseudomonas Infection
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by Pseudomonas Infection and healthy control cells in the Lung Tissue cell type.
Analysis URLhttp://genemania.org/#/search/human/RPS10|RPL19|HSPA1A|RPS15A|IRAK1|RPSA|RPS23|PABPC1|RPL21|RPL41|RPLP0|RLIM|VIM|RPS8|EIF3CL|TM4SF4|RPS18|LOC728026|RPN2|S100A6|NGFRAP1|AGR2|RPL30|EIF3L|S100P
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:170
Cell TypeLung Tissue
Disease NamePseudomonas Infection
Organismhuman
UMLS CUIC0033817
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM14498, GSM14499, GSM14500, GSM14501
Perturbed SamplesGSM14502, GSM14503, GSM14504, GSM14505, GSM14509, GSM14510, GSM14511, GSM14512
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE923
Gene Expression Omnibus
Mucoid and motile Pseudomonas aeruginosa infected lung epithelial cell comparison
7
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