Interaction network and enrichment analysis of genes upregulated in JRA - Juvenile rheumatoid arthritis
Canned Analysis
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General Information
AccessionDCA00033044
TitleInteraction network and enrichment analysis of genes upregulated in JRA - Juvenile rheumatoid arthritis
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by JRA - Juvenile rheumatoid arthritis and healthy control cells in the Peripheral blood mononuclear cell cell type.
Analysis URLhttp://genemania.org/#/search/human/HBA2|HIST2H2BE|PLAC8|PIM1|PIM3|PPBP|IER2|HIST1H2AC|IFI44L|S100A8|STRADB|ADM|HBG2|IFITM3|IFI44|CMPK2|ADAR|S100A9|SELL|MXI1|CYAT1|RSAD2|CD69|GNG10|GPR171
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:176
Cell TypePeripheral blood mononuclear cell
Disease NameJRA - Juvenile rheumatoid arthritis
Organismhuman
UMLS CUIC0553662
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM187584, GSM187585, GSM187586, GSM187587, GSM187588, GSM187589, GSM187590, GSM187591, GSM187592, GSM187593, GSM187594, GSM187595, GSM187596, GSM187597, GSM187598, GSM187599, GSM187600, GSM187601, GSM187602, GSM187603, GSM187604, GSM187605, GSM187606, GS
Perturbed SamplesGSM187614, GSM187615, GSM187616, GSM187617, GSM187618, GSM187619, GSM187620, GSM187621, GSM187622, GSM187623, GSM187624, GSM187625, GSM187626, GSM187627, GSM187628, GSM187629, GSM187630
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE7753
Gene Expression Omnibus
Gene Expression Profiling in Peripheral Blood in Untreated New Onset Systemic Juvenile Idiopathic Arthritis
7
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