Interaction network and enrichment analysis of genes downregulated in Nephrolithiasis
Canned Analysis
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General Information
AccessionDCA00033061
TitleInteraction network and enrichment analysis of genes downregulated in Nephrolithiasis
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by Nephrolithiasis and healthy control cells in the Kidney cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Cyp4a31|Cyp2a5|Hsd3b4|Ttr|Cyp4a12a|Rnase4|Cyp4a14|Ehhadh|Acaa1b|Cml5|Plin2|Ftl1|Arl6ip1|Vnn1|Igkv6-23|Asl|Slc7a7|Aadac|Cyp2d12|Psmd6|Gsta2|LOC544903|Lpl|Slc6a19|Alpl
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:187
Cell TypeKidney
Disease NameNephrolithiasis
Organismmouse
UMLS CUIC0392525
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM256959, GSM256960, GSM256961
Perturbed SamplesGSM256956, GSM256957, GSM256958
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE10162
Gene Expression Omnibus
Dent disease model: renal proximal tubules
12
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