Interaction network and enrichment analysis of genes downregulated in synovial sarcoma
Canned Analysis
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General Information
AccessionDCA00033163
TitleInteraction network and enrichment analysis of genes downregulated in synovial sarcoma
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by synovial sarcoma and healthy control cells in the Synovial Membrane cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Tnnt3|Mylpf|Ckm|Pvalb|Atp2a1|Cox6a2|Cox8b|Actn3|Ckmt2|Sar1b|Myot|Acta1|Mybpc2|Cox5a|Cycs|Ldha|Usmg5|Myl1|Tcap|Hspb6|Hbb-bs|Fth1|Chchd10|Ybx3|Atp5j2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:22
Cell TypeSynovial Membrane
DO IDDOID:5485
Disease Namesynovial sarcoma
Organismmouse
UMLS CUIC0039101
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM148507, GSM148508, GSM148509, GSM148510
Perturbed SamplesGSM148511, GSM148512, GSM148513, GSM148514, GSM148515
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE6461
Gene Expression Omnibus
Synovial sarcoma model
7
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