Interaction network and enrichment analysis of genes downregulated in ulcerative colitis
Canned Analysis
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General Information
AccessionDCA00033263
TitleInteraction network and enrichment analysis of genes downregulated in ulcerative colitis
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by ulcerative colitis and healthy control cells in the Sigmoid colon cell type.
Analysis URLhttp://genemania.org/#/search/human/NLK|NAPA|GLOD5|RBM18|METTL17|SLC35F5|RBPJ|CCDC106|PDDC1|CACHD1|LINC00094|CIRBP|C10orf62|TLE1|LOC100129721|HSD17B6|FAM210A|OTUD6B|UBE2J1|USP33|MSH6|IL10RB-AS1|PRPH|TMEM216|CHSY1
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:264
Cell TypeSigmoid colon
DO IDDOID:8577
Disease Nameulcerative colitis
Organismhuman
UMLS CUIC0009324
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM29595, GSM29596, GSM29597, GSM29598, GSM29599, GSM29600, GSM29601, GSM29602, GSM29603, GSM29604, GSM29605
Perturbed SamplesGSM29616, GSM29617, GSM29618, GSM29619, GSM29620, GSM29621, GSM29622, GSM29623, GSM29624, GSM29625
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE1710
Gene Expression Omnibus
Crohn disease and ulcerative colitis comparison
19
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