Interaction network and enrichment analysis of genes downregulated in Squamous cell carcinoma of mouth
Canned Analysis
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General Information
AccessionDCA00033313
TitleInteraction network and enrichment analysis of genes downregulated in Squamous cell carcinoma of mouth
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by Squamous cell carcinoma of mouth and healthy control cells in the Oropharynx Epithelium cell type.
Analysis URLhttp://genemania.org/#/search/human/CRNN|ENDOU|KRT76|RHCG|MAL|TGM3|LOR|KRT1|SCEL|SPRR3|FLG|SPINK5|KRT4|CRCT1|HOPX|CWH43|IVL|KLK12|GPX3|SERPINB2|EPHX3|DSG1|COBL|ALOX12B|TPPP3
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:295
Cell TypeOropharynx Epithelium
Disease NameSquamous cell carcinoma of mouth
Organismhuman
UMLS CUIC0585362
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM80476, GSM80477, GSM80520, GSM80521
Perturbed SamplesGSM80460, GSM80461, GSM80462, GSM80463, GSM80464, GSM80465, GSM80466, GSM80467, GSM80468, GSM80469, GSM80470, GSM80471, GSM80472, GSM80473, GSM80474, GSM80475
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE3524
Gene Expression Omnibus
Oral squamous cell carcinoma
7
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