Interaction network and enrichment analysis of genes downregulated in acne
Canned Analysis
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General Information
AccessionDCA00033315
TitleInteraction network and enrichment analysis of genes downregulated in acne
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by acne and healthy control cells in the Sebocyte cell type.
Analysis URLhttp://genemania.org/#/search/human/KRT5|RPL12|RPL27A|NPM1|RPL7|RPS2|RPSAP58|SNORA21|EEF1A1|EEF2|S100A10|AHNAK|RPL6|ANXA2P3|RBM3|RPL8|RPL11|RPL35|RPL4|RPL21|RPS13|KRT6A|RPL3|RPL9|HMGN2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:297
Cell TypeSebocyte
DO IDDOID:6543
Disease Nameacne
Organismhuman
UMLS CUIC0702166
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM263915, GSM263916, GSM263917
Perturbed SamplesGSM263918, GSM263919, GSM263920
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE10432
Gene Expression Omnibus
13-cis retinoic acid effect on SEB-1 sebocyte cell line
12
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