Interaction network and enrichment analysis of genes upregulated in Helicobacter pylori gastrointestinal tract infection
Canned Analysis
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General Information
AccessionDCA00033338
TitleInteraction network and enrichment analysis of genes upregulated in Helicobacter pylori gastrointestinal tract infection
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by Helicobacter pylori gastrointestinal tract infection and healthy control cells in the Gastric Tissue cell type.
Analysis URLhttp://genemania.org/#/search/human/ICOSLG|GAPDH|CD274|AMHR2|SLAMF1|BACE1|YWHAZ|CDH1|SOCS1|HLA-A|RPSA|CD6|IRF1|PRKCB|TYMP|PTPRC|MERTK|JUNB|PAK2|B2M|NAMPT|CLEC11A|CXCR4|BCL3|PECAM1
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:303
Cell TypeGastric Tissue
Disease NameHelicobacter pylori gastrointestinal tract infection
Organismhuman
UMLS CUIC0585625
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM12764, GSM12765, GSM12766, GSM8906, GSM8908, GSM8911, GSM8913, GSM8914, GSM8916, GSM8918, GSM8919, GSM8922
Perturbed SamplesGSM12762, GSM12763, GSM12767, GSM8905, GSM8907, GSM8909, GSM8910, GSM8912, GSM8915, GSM8917, GSM8920, GSM8921, GSM8923, GSM8924, GSM8925
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE581
Gene Expression Omnibus
Gastric mucosa immune response to Helicobacter pylori
7
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