Interaction network and enrichment analysis of genes downregulated in hepatitis C
Canned Analysis
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General Information
AccessionDCA00033349
TitleInteraction network and enrichment analysis of genes downregulated in hepatitis C
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by hepatitis C and healthy control cells in the Hepatocyte cell type.
Analysis URLhttp://genemania.org/#/search/human/RPS11|AFP|FABP1|TTR|FTL|EEF1B2|FGB|RPL27A|FGG|HSPD1|ENO1|CCL20|PLA2G2A|IGFBP1|APOA2|AKR1C2|RPL19|APOM|GPX3|EEF1A1|RPS18|RPS16|APOH|AHSG|FN1
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:309
Cell TypeHepatocyte
DO IDDOID:1883
Disease Namehepatitis C
Organismhuman
UMLS CUIC0019196
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM37564, GSM37565, GSM37566
Perturbed SamplesGSM37561, GSM37562, GSM37563
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE2067
Gene Expression Omnibus
Hepatitis C virus core protein effect on hepatocyte cell line
7
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