Interaction network and enrichment analysis of genes downregulated in Rhinovirus infection
Canned Analysis
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General Information
AccessionDCA00033377
TitleInteraction network and enrichment analysis of genes downregulated in Rhinovirus infection
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by Rhinovirus infection and healthy control cells in the Nose cell type.
Analysis URLhttp://genemania.org/#/search/human/HLA-DRB4|BPIFB1|HLA-DPB1|RARRES1|CYP4B1|HBA2|KRT5|EPHX1|ADH1C|TSPAN13|MUC5AC|EIF3CL|SLC25A5|KRT18|IRX3|HMGN3|SH3KBP1|ACTG1|RPS26|C15orf48|ANKRD36B|MSMB|LYZ|FTL|CXCL8
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:324
Cell TypeNose
Disease NameRhinovirus infection
Organismhuman
UMLS CUIC0276447
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM286649, GSM286650, GSM286651, GSM286655, GSM286656, GSM286657, GSM286658, GSM286659, GSM286660, GSM286661, GSM286662, GSM286663, GSM286664, GSM286665, GSM286666, GSM286670, GSM286671, GSM286672, GSM286673, GSM286674, GSM286675, GSM286676, GSM286677, GS
Perturbed SamplesGSM286646, GSM286647, GSM286648, GSM286652, GSM286653, GSM286654, GSM286667, GSM286668, GSM286669, GSM286679, GSM286680, GSM286681, GSM286682, GSM286683, GSM286684, GSM286691, GSM286692, GSM286693, GSM286697, GSM286698, GSM286699, GSM286700, GSM286701, GS
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE11348
Gene Expression Omnibus
Gene expression profiles during in vivo human rhinovirus infection: insights into the host response.
7
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