Interaction network and enrichment analysis of genes downregulated in Sendai virus infection
Canned Analysis
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General Information
AccessionDCA00033409
TitleInteraction network and enrichment analysis of genes downregulated in Sendai virus infection
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by Sendai virus infection and healthy control cells in the macrophage cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Lgals3|Tyrobp|Spp1|Gm13826|Ctsl|Ctsz|Rps11|Rpl5|Rpl3|Ctsd|Rplp0|Anxa1|Ybx1|Lgals1|Fth1|Creg1|Clec4d|C1qa|Akr1a1|Itm2b|Tpt1|Cst3|Rpl18|Glmp|Rpl7a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:336
Cell Typemacrophage
Disease NameSendai virus infection
Organismmouse
UMLS CUIC1319860
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM64057, GSM64058
Perturbed SamplesGSM64059, GSM64060
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE2935
Gene Expression Omnibus
Macrophage response to viral infection
7
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