Interaction network and enrichment analysis of genes upregulated in allergic asthma
Canned Analysis
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General Information
AccessionDCA00033430
TitleInteraction network and enrichment analysis of genes upregulated in allergic asthma
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by allergic asthma and healthy control cells in the Lung Tissue cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Chil3|Igkv6-23|Chia1|Cd74|H2-Aa|Mmp12|Bpifb1|C3|Igkv4-58|Igkv4-59|Igkv4-91|Ctss|Chil1|H2-Eb1|Igkv4-70|Igkv4-74|Gm16710|Igj|LOC100046359|Pigr|C1qc|LOC100505009|LOC100505002|H2-Ab1|Gnb2l1
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:348
Cell TypeLung Tissue
DO IDDOID:9415
Disease Nameallergic asthma
Organismmouse
UMLS CUIC0155877
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM42223, GSM42224, GSM42225
Perturbed SamplesGSM42226, GSM42227, GSM42228
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE2276
Gene Expression Omnibus
Asthma model of prostaglandin E receptor EP3 effect on allergic inflammation
7
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