Interaction network and enrichment analysis of genes upregulated in Neurological pain disorder
Canned Analysis
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General Information
AccessionDCA00033450
TitleInteraction network and enrichment analysis of genes upregulated in Neurological pain disorder
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by Neurological pain disorder and healthy control cells in the Dorsal Root Ganglia cell type.
Analysis URLhttp://genemania.org/#/search/rat/Fth1|COX2|ND1|ND2|COX1|Nefm|Tuba1b|Hba2|CYTB|Tubb2a|Nefh|ND3|Tmsb4x|Stmn2|LOC689064|Rps29|LOC100360413|Ctsb|Hspa8|Calm2|Ndrg4|Ubb|Cst3|Lgals1|Vim
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:356
Cell TypeDorsal Root Ganglia
Disease NameNeurological pain disorder
Organismrat
UMLS CUIC0423704
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM375686, GSM375687, GSM375688
Perturbed SamplesGSM375689, GSM375690, GSM375691, GSM375692, GSM375693, GSM375694
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE15041
Gene Expression Omnibus
Postnatal developmental changes in Sprague-Dawley rats in the model of neuropathic pain 'spare nerve injury'
7
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