Interaction network and enrichment analysis of genes downregulated in Infection by Aspergillus fumigatus
Canned Analysis
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General Information
AccessionDCA00033495
TitleInteraction network and enrichment analysis of genes downregulated in Infection by Aspergillus fumigatus
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by Infection by Aspergillus fumigatus and healthy control cells in the Dendritic cell cell type.
Analysis URLhttp://genemania.org/#/search/human/HLA-DQA1|CD1A|CTSL|TGFBI|C15orf48|CEBPB|HMOX1|CCL4|FABP5|ATP1B1|LOC100133583|C5AR1|NFKBIZ|ZFP36|IL6|IL7R|CECR1|RPS4Y1|IL1B|IER3|CCL23|LOC100507328|CCL15-CCL14|ARRDC4|MMP9
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:386
Cell TypeDendritic cell
Disease NameInfection by Aspergillus fumigatus
Organismhuman
UMLS CUIC0276655
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM160530, GSM160534
Perturbed SamplesGSM160532, GSM160536
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE6965
Gene Expression Omnibus
Immature dendritic cell response to Aspergillus fumigatus infection in vitro
7
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