Interaction network and enrichment analysis of genes downregulated in endometriosis
Canned Analysis
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General Information
AccessionDCA00033511
TitleInteraction network and enrichment analysis of genes downregulated in endometriosis
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by endometriosis and healthy control cells in the Endometrial specimens from women with endometriosis - Proliferative cell type.
Analysis URLhttp://genemania.org/#/search/human/RPS14P3|SLC25A5|RPL36A|PTMA|RPL12|RPL8|EIF3CL|CD81|EEF2|APCDD1|SPON2|ID3|IGFBP4|RPS10|IER2|HLA-B|RPL36|RPL39|PAMR1|RPL32|PPIB|HLA-C|RPS18|ISLR|HLA-A
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:945
Cell TypeEndometrial specimens from women with endometriosis - Proliferative
DO IDDOID:289
Disease Nameendometriosis
Organismhuman
UMLS CUIC0014175
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM150196, GSM150197, GSM150198, GSM150199, GSM150201
Perturbed SamplesGSM150190, GSM150191, GSM150192, GSM150193, GSM150194, GSM150195
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE6364
Gene Expression Omnibus
Endometriosis
28
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