Interaction network and enrichment analysis of genes downregulated in Spinal Cord Injury
Canned Analysis
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General Information
AccessionDCA00033573
TitleInteraction network and enrichment analysis of genes downregulated in Spinal Cord Injury
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by Spinal Cord Injury and healthy control cells in the CNS - Spinal Cord (MMHCC) cell type.
Analysis URLhttp://genemania.org/#/search/rat/Nefl|Tecr|Nefm|Eef1a2|Prkar1b|Stxbp1|Atp1a3|Spock2|Uchl1|Hmgcs1|Ndrg4|Dnm1|Stx1b|Syp|Hba2|Mobp|Msmo1|Snrpn|Nefh|Pea15|Ywhah|Ncdn|Aldoa|Tpi1|Ywhag
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:426
Cell TypeCNS - Spinal Cord (MMHCC)
Disease NameSpinal Cord Injury
Organismrat
UMLS CUIC0037929
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM49936, GSM49937, GSM49938
Perturbed SamplesGSM49933, GSM49934, GSM49935
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE2599
Gene Expression Omnibus
Spinal cord contusion
7
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