Interaction network and enrichment analysis of genes downregulated in Rotavirus infection of children
Canned Analysis
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General Information
AccessionDCA00033579
TitleInteraction network and enrichment analysis of genes downregulated in Rotavirus infection of children
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by Rotavirus infection of children and healthy control cells in the Peripheral blood mononuclear cell cell type.
Analysis URLhttp://genemania.org/#/search/human/TPT1|RPL9|SNORA21|RPL5|RPL4|RPL23A|RPL34|LOC100510519|RPL7|LYZ|RPL19|RPS7|HBB|RPS8|RPL11|EEF1B2|EEF1G|RPS27A|NACA|RPS4X|RPL23|RPS10|RPLP2|RPL32|RPL6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:43
Cell TypePeripheral blood mononuclear cell
Disease NameRotavirus infection of children
Organismhuman
UMLS CUIC1442797
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM52859, GSM52860, GSM52861, GSM52862, GSM52863, GSM52864, GSM52865, GSM52866
Perturbed SamplesGSM52867, GSM52868, GSM52869, GSM52870, GSM52871, GSM52872, GSM52873, GSM52874, GSM52875, GSM52876
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE2729
Gene Expression Omnibus
Acute rotavirus infection: peripheral blood mononuclear cells
7
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