Interaction network and enrichment analysis of genes upregulated in dengue hemorrhagic fever
Canned Analysis
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General Information
AccessionDCA00033610
TitleInteraction network and enrichment analysis of genes upregulated in dengue hemorrhagic fever
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by dengue hemorrhagic fever and healthy control cells in the Whole Blood cell type.
Analysis URLhttp://genemania.org/#/search/human/IFI27|LOC100290146|CYAT1|IGHA2|PLAC8|RPS4Y1|GZMB|TXNDC5|LOC100291682|TMSB10|ISG15|HMGN2|IFI6|IGJ|IFI30|PSME2|PPIB|MX1|PSMA6|LGALS1|LAP3|LOC100291464|LDHA|GAPDH|HIST1H4C
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgaribr01
CREEDS IDdz:447
Cell TypeWhole Blood
DO IDDOID:12206
Disease Namedengue hemorrhagic fever
Organismhuman
UMLS CUIC0019100
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM1253075, GSM1253076, GSM1253077, GSM1253078, GSM1253079, GSM1253083
Perturbed SamplesGSM1253044, GSM1253047, GSM1253050, GSM1253051, GSM1253053
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE51808
Gene Expression Omnibus
Acute Dengue patients: whole blood
21
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