Interaction network and enrichment analysis of genes upregulated in polycystic ovary syndrome
Canned Analysis
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General Information
AccessionDCA00033694
TitleInteraction network and enrichment analysis of genes upregulated in polycystic ovary syndrome
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by polycystic ovary syndrome and healthy control cells in the Stromal cells cell type.
Analysis URLhttp://genemania.org/#/search/human/LRP2|NDNF|KIAA1210|LSAMP|GRIA4|SNORD113-4|CXCL12|LRRTM4|F13A1|ITPR2|HSPA6|GABRA3|IGF1|SNORD30|PDGFRA|ANO4|ALDH1A2|SNORA29|STK19|C4B|HCN1|FREM1|VLDLR-AS1|RGS4|ABCA8
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:560
Cell TypeStromal cells
DO IDDOID:11612
Disease Namepolycystic ovary syndrome
Organismhuman
UMLS CUIC0032460
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM1174410, GSM1174411, GSM1174415, GSM1174422
Perturbed SamplesGSM1174423, GSM1174426, GSM1174431, GSM1174434
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE48301
Gene Expression Omnibus
Polycystic ovary syndrome: proliferative phase endometrial cell types
42
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