Interaction network and enrichment analysis of genes downregulated in glomerulosclerosis
Canned Analysis
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General Information
AccessionDCA00033747
TitleInteraction network and enrichment analysis of genes downregulated in glomerulosclerosis
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by glomerulosclerosis and healthy control cells in the OVE26 type 1 cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Ren2|Sfrp2|Cdkn1c|Umod|Gm5526|Gm8894|Ptma|Dbp|Egf|Rpl10|Gm12657|H2-L|Rpl27a|Cst3|Zfp526|Emcn|Laptm4a|Rpl31|Chchd2|Nr2f1|Cyp26b1|Rps23|Rpl31-ps17|Rps3a2|B2m
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatoralanstern
CREEDS IDdz:492
Cell TypeOVE26 type 1
DO IDDOID:0050851
Disease Nameglomerulosclerosis
Organismmouse
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM519444, GSM519445, GSM519766
Perturbed SamplesGSM519813, GSM519814, GSM519815, GSM519816
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE20844
Gene Expression Omnibus
Diabetic OVE26 glomerulus
7
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