Interaction network and enrichment analysis of genes upregulated in swine influenza
Canned Analysis
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General Information
AccessionDCA00033756
TitleInteraction network and enrichment analysis of genes upregulated in swine influenza
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by swine influenza and healthy control cells in the primary lung bronchial epithelial cells cell type.
Analysis URLhttp://genemania.org/#/search/human/ISG15|IFIT1|IFITM1|IFI6|CXCL10|IFIT3|MX1|IFI27|IFITM3|RSAD2|IFIT2|CMPK2|IFITM2|CXCL11|OAS1|NUPR1|IFI44L|MX2|IDO1|TNFSF10|LAP3|NT5C3A|UBE2L6|TRIM22|MT2A
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatoralanstern
CREEDS IDdz:498
Cell Typeprimary lung bronchial epithelial cells
DO IDDOID:0050211
Disease Nameswine influenza
Organismhuman
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM1179373, GSM1179374, GSM1179375
Perturbed SamplesGSM1179364, GSM1179365, GSM1179366, GSM1179367, GSM1179368, GSM1179369, GSM1179370, GSM1179371, GSM1179372
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE48466
Gene Expression Omnibus
Pandemic and seasonal H1N1 influenza virus infections of bronchial epithelial cells in vitro
7
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