Interaction network and enrichment analysis of genes upregulated in hepatitis C
Canned Analysis
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General Information
AccessionDCA00033938
TitleInteraction network and enrichment analysis of genes upregulated in hepatitis C
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by hepatitis C and healthy control cells in the Huh7 hepatoma cells (infected with JFH-1 HCV) - 18 Hours post-infection cell type.
Analysis URLhttp://genemania.org/#/search/human/S100P|FGG|SNHG1|GARS|PSAT1|HSPA1A|CCL20|RPL3|DANCR|RPL32|RPL41|RPS18|CEBPB|NPM1|NME1|ATF4|AGT|NOP58|RPSA|CDK4|ALDH1A1|TSPAN13|FTL|AKR1B10|RPL12
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:599
Cell TypeHuh7 hepatoma cells (infected with JFH-1 HCV) - 18 Hours post-infection
DO IDDOID:1883
Disease Namehepatitis C
Organismhuman
UMLS CUIC0019196
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM523819, GSM523820, GSM523821
Perturbed SamplesGSM523805, GSM523806, GSM523807
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE20948
Gene Expression Omnibus
Hepatitis C Virus infection effect on Huh7 hepatoma cells: time course
35
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