Interaction network and enrichment analysis of genes downregulated in pancreatic ductal adenocarcinoma
Canned Analysis
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General Information
AccessionDCA00033951
TitleInteraction network and enrichment analysis of genes downregulated in pancreatic ductal adenocarcinoma
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by pancreatic ductal adenocarcinoma and healthy control cells in the Pancreatic tissue cell type.
Analysis URLhttp://genemania.org/#/search/human/REG1A|GCG|HBA2|SSR4|MT1HL1|SLC25A5|PRDX4|EEF1B2|DEFA5|RGS2|AMY2B|RPS5|PGA4|ERP27|MT2A|GKN1|ND2|MT1X|DEFA6|RPL21|AKR1B10|SST|PRSS3|LIPF|ALDH1A1
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curator
CREEDS ID
Cell Type
DO ID
Disease Name
Organism
UMLS CUI
Characteristic Direction parameters
Gene Set
Gene Set Size
Control Samples
Perturbed Samples
Tools used in the analysis

Keyword
Dataset Accession

GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis

Keyword
Tool Name

GSE15471
ICF cohort: Whole-tissue pancreatic ductal adenocarcinoma
7
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