Interaction network and enrichment analysis of genes downregulated in ductal carcinoma in situ
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00033953
TitleInteraction network and enrichment analysis of genes downregulated in ductal carcinoma in situ
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by ductal carcinoma in situ and healthy control cells in the Mammary gland cell type.
Analysis URLhttp://genemania.org/#/search/human/HBA2|CFD|PLIN1|IGHA2|ADIRF|LPL|LEP|FABP4|CAV1|AOC3|KRT14|S100A4|PLIN4|IGJ|GPX3|G0S2|ADIPOQ|ND2|TXNIP|ALDH2|RPS26|FHL1|GPX4|RPL21|ACSL1
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:605
Cell TypeMammary gland
DO IDDOID:0060074
Disease Nameductal carcinoma in situ
Organismhuman
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM535613, GSM535614, GSM535615, GSM535616, GSM535617
Perturbed SamplesGSM535604, GSM535605, GSM535606, GSM535607, GSM535608, GSM535609, GSM535610, GSM535611, GSM535612
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE21422
Gene Expression Omnibus
Ductal carcinoma in situ: mammary gland
14
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.