Interaction network and enrichment analysis of genes downregulated in pancreatic invasive intraductal papillary-mucinous carcinoma
Canned Analysis
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General Information
AccessionDCA00033963
TitleInteraction network and enrichment analysis of genes downregulated in pancreatic invasive intraductal papillary-mucinous carcinoma
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by pancreatic invasive intraductal papillary-mucinous carcinoma and healthy control cells in the Epithelial cells (pancreatic duct) cell type.
Analysis URLhttp://genemania.org/#/search/human/CPB1|PRSS2|CTRB2|PNLIP|REG1B|PRSS3|REG1A|CELA3A|PRSS3P2|PRSS1|AMY2B|CPA2|PLA2G1B|CLPS|RPL3|CPA1|RPS18|SPINK1|RPS10|RPS4Y1|CELA2A|CTRC|EEF1G|INS|ND2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:610
Cell TypeEpithelial cells (pancreatic duct)
DO IDDOID:8150
Disease Namepancreatic invasive intraductal papillary-mucinous carcinoma
Organismhuman
UMLS CUIC1518871
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM490138, GSM490139, GSM490140, GSM490141, GSM490142, GSM490143, GSM490144
Perturbed SamplesGSM490157, GSM490158, GSM490159
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE19650
Gene Expression Omnibus
Multistep pancreatic carcinogenesis: epithelial cells
21
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