Interaction network and enrichment analysis of genes upregulated in papillary thyroid carcinoma
Canned Analysis
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General Information
AccessionDCA00034022
TitleInteraction network and enrichment analysis of genes upregulated in papillary thyroid carcinoma
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by papillary thyroid carcinoma and healthy control cells in the Papillary thyroid carcinoma tumors (without a BRAF mutation) and Normal thyroid specimens cell type.
Analysis URLhttp://genemania.org/#/search/human/TG|CTSB|FN1|PDK4|HSP90B1|CANX|APLP2|SPARC|SNORA38B|ARRDC3|NPNT|GAPDH|ANXA1|CTNNB1|LMAN2|HSPA5|NPC2|TMBIM6|PDIA3P1|APP|LAPTM4A|RGS5|PCSK2|CD44|CALR
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:652
Cell TypePapillary thyroid carcinoma tumors (without a BRAF mutation) and Normal thyroid specimens
DO IDDOID:3969
Disease Namepapillary thyroid carcinoma
Organismhuman
UMLS CUIC0238463
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM1327256, GSM1327257, GSM1327258, GSM1327259, GSM1327260, GSM1327261
Perturbed SamplesGSM1327231, GSM1327232, GSM1327233, GSM1327234, GSM1327235, GSM1327236, GSM1327237, GSM1327238, GSM1327239, GSM1327240, GSM1327241
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE54958
Gene Expression Omnibus
Expression profiling in proliferative thyroid lesions of different histologies and normal thyroid tissue
14
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