Interaction network and enrichment analysis of genes downregulated in renal cell carcinoma
Canned Analysis
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General Information
AccessionDCA00034045
TitleInteraction network and enrichment analysis of genes downregulated in renal cell carcinoma
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by renal cell carcinoma and healthy control cells in the Blood myelomonocytic cells from RCC and Healthy blood myelomonocytic cells cell type.
Analysis URLhttp://genemania.org/#/search/human/MMP9|ITGB2|LIPA|ARHGDIB|CXCL5|TUBA1B|TMSB10|LAMP1|ATP6AP1|ATP5B|CYP27A1|FABP4|GLRX|LTA4H|ENO1|NPC2|OAZ1|TFRC|CSF1R|PLA2G7|PPT1|HEXB|CALM2|SLC25A5|SEPT9
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:664
Cell TypeBlood myelomonocytic cells from RCC and Healthy blood myelomonocytic cells
DO IDDOID:4450
Disease Namerenal cell carcinoma
Organismhuman
UMLS CUIC0007134
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM941952, GSM941953, GSM941954, GSM941955
Perturbed SamplesGSM941956, GSM941957, GSM941959, GSM941960
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE38424
Gene Expression Omnibus
Analysis of blood myelomonocytic cells from RCC patients
7
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