Interaction network and enrichment analysis of genes upregulated in Lung Injury
Canned Analysis
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General Information
AccessionDCA00034058
TitleInteraction network and enrichment analysis of genes upregulated in Lung Injury
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by Lung Injury and healthy control cells in the Lung Tissue cell type.
Analysis URLhttp://genemania.org/#/search/human/AKR1B10|AKR1C2|LDHA|EEF1A1|RPL5|RPS3|RPL36A|RPS19|RPS15|AKR1C1|PRDX1|S100A6|ACTB|RPL23A|RPS18|RPL7|RPL32|RPS10|PKM|CAPN2|RPS8|ALDH3A1|GAPDH|SLC7A5|ALDH1A1
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:67
Cell TypeLung Tissue
Disease NameLung Injury
Organismhuman
UMLS CUIC0273115
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM26477, GSM26478, GSM26479, GSM26480
Perturbed SamplesGSM26485, GSM26486, GSM26487, GSM26488
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE1541
Gene Expression Omnibus
Alveolar epithelial cell line A549 response to acute lung injury causing stimuli: time course
7
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