Interaction network and enrichment analysis of genes upregulated in peripartum cardiomyopathy
Canned Analysis
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General Information
AccessionDCA00034076
TitleInteraction network and enrichment analysis of genes upregulated in peripartum cardiomyopathy
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by peripartum cardiomyopathy and healthy control cells in the Left Ventricle Apex Tissue cell type.
Analysis URLhttp://genemania.org/#/search/human/TXNIP|ANKRD1|HSPA8|HSPB1|FABP3|UBC|MIR675|SPARC|MB|CD36|SNORD13|LPL|MYOM2|EIF1AY|TECRL|HSPA1A|HSP90AB1|EGLN3|LUM|MYL12B|USMG5|HSP90B1|PDLIM3|HSPB8|NPPB
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgswaminath
CREEDS IDdz:817
Cell TypeLeft Ventricle Apex Tissue
DO IDDOID:9997
Disease Nameperipartum cardiomyopathy
Organismhuman
UMLS CUIC0877208
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM1053922, GSM1053929, GSM1053939, GSM1053940, GSM1053942
Perturbed SamplesGSM1053914, GSM1053915, GSM1053916, GSM1053917, GSM1053918, GSM1053919, GSM1053920, GSM1053921, GSM1053923, GSM1053924, GSM1053925, GSM1053926, GSM1053927, GSM1053928, GSM1053930, GSM1053931, GSM1053932, GSM1053933, GSM1053934, GSM1053935, GSM1053936, GSM
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE42955
Gene Expression Omnibus
Dilated cardiomyopathy: left ventricle apex
14
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