Interaction network and enrichment analysis of genes downregulated in diffuse large B-cell lymphoma
Canned Analysis
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General Information
AccessionDCA00034103
TitleInteraction network and enrichment analysis of genes downregulated in diffuse large B-cell lymphoma
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by diffuse large B-cell lymphoma and healthy control cells in the marginal lymphoma, BRD2 transgenic cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Pgk1|Ldha|Eno1b|Gapdh|Mif|Pkm|Npm1|Atp5g3|Tpi1|Ifi27l2a|Hspd1|Gm6793|Tcp1|C1qbp|Gm3601|Nme2|Pgam1|Ms4a4c|Cox5a|Cd83|Eef1g|Kpna2|Gm11847|Hsp90ab1|Pebp1
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatornbongio
CREEDS IDdz:686
Cell Typemarginal lymphoma, BRD2 transgenic
DO IDDOID:0050745
Disease Namediffuse large B-cell lymphoma
Organismmouse
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM142399, GSM142422, GSM142423
Perturbed SamplesGSM142402, GSM142403, GSM142404, GSM142407, GSM142408, GSM142409
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE6136
Gene Expression Omnibus
Diffuse large B cell lymphoma model
33
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