Interaction network and enrichment analysis of genes downregulated in adenosquamous cell lung carcinoma
Canned Analysis
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General Information
AccessionDCA00034227
TitleInteraction network and enrichment analysis of genes downregulated in adenosquamous cell lung carcinoma
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by adenosquamous cell lung carcinoma and healthy control cells in the Primary lung tumor and Normal lung cell type.
Analysis URLhttp://genemania.org/#/search/human/SPARCL1|MRC1|TEK|GGTA1P|CH25H|EMCN|FIGF|GPR183|SELE|CPB2|ATP1A2|EGR2|MNDA|P2RY14|A2M|PRG4|C11orf96|PROK2|CYP4B1|DEFA3|SELP|CD69|SLC6A4|NLRC4|IL33
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:731
Cell TypePrimary lung tumor and Normal lung
DO IDDOID:4829
Disease Nameadenosquamous cell lung carcinoma
Organismhuman
UMLS CUIC0279557
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM1253940, GSM1253941, GSM1253942, GSM1253943
Perturbed SamplesGSM1253891, GSM1253892, GSM1253893, GSM1253894
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE51852
Gene Expression Omnibus
Lung adenocarcinoma subtypes definable by lung development-related miRNA expression profiles in association with clinicopathologic features [mRNA anal...
28
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