Interaction network and enrichment analysis of genes downregulated in myelodysplastic syndrome
Canned Analysis
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General Information
| Accession | DCA00034261 |
| Title | Interaction network and enrichment analysis of genes downregulated in myelodysplastic syndrome |
| Description | The analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by myelodysplastic syndrome and healthy control cells in the CD34+ hematopoietic stem cells (refractory anemia with ringed sideroblasts) cell type. |
| Analysis URL | http://genemania.org/#/search/human/DEFA1B|CXCR4|TUBA1A|LAPTM5|KLF10|TOP2B|DNTT|TMEM123|HMGB1|HMGN2|H2AFZ|RNASE2|UHRF1|LINC00341|EIF3E|LOC100510649|TPT1|ELANE|RPS25|GAPDH|HLA-DRA|RGS2|SRP14|LDHA|UBB |
| Upload Date | September 20, 2017 |
| Uploader | maayanlab |
Metadata
| Analysis Curator | cadimo |
| CREEDS ID | dz:750 |
| Cell Type | CD34+ hematopoietic stem cells (refractory anemia with ringed sideroblasts) |
| DO ID | DOID:0050908 |
| Disease Name | myelodysplastic syndrome |
| Organism | human |
Characteristic Direction parameters
| Gene Set | downregulated |
| Gene Set Size | 50 |
| Control Samples | GSM483480, GSM483481, GSM483482, GSM483483, GSM483484, GSM483485, GSM483486, GSM483487, GSM483488, GSM483489, GSM483490, GSM483491, GSM483492, GSM483493, GSM483494, GSM483495, GSM483496 |
| Perturbed Samples | GSM483297, GSM483298, GSM483299, GSM483306, GSM483309, GSM483314, GSM483316, GSM483321, GSM483324, GSM483326, GSM483335, GSM483340, GSM483342, GSM483345, GSM483346, GSM483355, GSM483357, GSM483359, GSM483360, GSM483382, GSM483383, GSM483387, GSM483392, GS |
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