Interaction network and enrichment analysis of genes downregulated in Heart Injury
Canned Analysis
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General Information
AccessionDCA00034265
TitleInteraction network and enrichment analysis of genes downregulated in Heart Injury
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by Heart Injury and healthy control cells in the Myocardial tissue cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Hba-a2|Hbb-bs|Fhl2|Acta1|Eno3|Pdha1|Eef1a2|Got1|Ndufa1|Ckm|Rpl39-ps|Acadm|Uqcrfs1|Uqcr11|Hspb1|Vdac3|Mybpc3|Ptgds|Cox8b|Casq2|Uqcrc1|Ldhb|Coq9|Pgam2|2010107E04Rik
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:75
Cell TypeMyocardial tissue
Disease NameHeart Injury
Organismmouse
UMLS CUIC0018805
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM106378, GSM106379
Perturbed SamplesGSM106380, GSM106381, GSM106382, GSM106383, GSM106384, GSM106385
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE4710
Gene Expression Omnibus
Heart response to injury: time course
7
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